7m0t B 3.19 BS01 3EW B 1 G79 K97 M143 D208 F209 G210 V211 S212 L215 I216 M219 G38 K56 M102 D167 F168 G169 V170 S171 L174 I175 M178 D190 K192 N195 D208 D217 T226 D149 K151 N154 D167 D176 T185 2.7.12.2 0000165,0000187,0004672,0004674,0004708,0004712,0004713,0005078,0005515,0005524,0005634,0005737,0005739,0005769,0005770,0005783,0005794,0005813,0005816,0005829,0005856,0005886,0005925,0006468,0006935,0007165,0007507,0008285,0010628,0014044,0016020,0016310,0021697,0030182,0030216,0030295,0030878,0032872,0035987,0038133,0042552,0043410,0043539,0044342,0045893,0048009,0048538,0048679,0048870,0050772,0060020,0060324,0060425,0060440,0060502,0060674,0060711,0070371,0070374,0071902,0090170,0090398,0097110,0106310,1903226,2000641 IC50=80nM, Kd=99nM Q02750 34470822 401 LDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDAMANAFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQ 7m0t B 3.19 BS02 ANP B 1 G75 A76 G77 N78 V82 K97 M146 S150 Q153 K192 S194 L197 G34 A35 G36 N37 V41 K56 M105 S109 Q112 K151 S153 L156 D190 K192 N195 D208 D217 T226 D149 K151 N154 D167 D176 T185 2.7.12.2 0000165,0000187,0004672,0004674,0004708,0004712,0004713,0005078,0005515,0005524,0005634,0005737,0005739,0005769,0005770,0005783,0005794,0005813,0005816,0005829,0005856,0005886,0005925,0006468,0006935,0007165,0007507,0008285,0010628,0014044,0016020,0016310,0021697,0030182,0030216,0030295,0030878,0032872,0035987,0038133,0042552,0043410,0043539,0044342,0045893,0048009,0048538,0048679,0048870,0050772,0060020,0060324,0060425,0060440,0060502,0060674,0060711,0070371,0070374,0071902,0090170,0090398,0097110,0106310,1903226,2000641 Q02750 34470822 402 LDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDAMANAFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQ 7m0t B 3.19 BS03 MG B 1 N195 D208 N154 D167 D190 K192 N195 D208 D217 T226 D149 K151 N154 D167 D176 T185 2.7.12.2 0000165,0000187,0004672,0004674,0004708,0004712,0004713,0005078,0005515,0005524,0005634,0005737,0005739,0005769,0005770,0005783,0005794,0005813,0005816,0005829,0005856,0005886,0005925,0006468,0006935,0007165,0007507,0008285,0010628,0014044,0016020,0016310,0021697,0030182,0030216,0030295,0030878,0032872,0035987,0038133,0042552,0043410,0043539,0044342,0045893,0048009,0048538,0048679,0048870,0050772,0060020,0060324,0060425,0060440,0060502,0060674,0060711,0070371,0070374,0071902,0090170,0090398,0097110,0106310,1903226,2000641 Q02750 34470822 403 LDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDAMANAFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQ