6npu B 2.33 BS01 STI B 1 L267 Y272 V275 A288 K290 E305 V308 M309 V318 I332 T334 F336 M337 I379 H380 A399 D400 F401 L16 Y21 V24 A37 K39 E48 V51 M52 V61 I75 T77 F79 M80 I122 H123 A142 D143 F144 D382 A384 R386 N387 D400 P421 D125 A127 R129 N130 D143 P149 2.7.10.2 0004672,0004713,0005524,0006468 IC50=38nM, Kd=44nM, Ki=13nM, EC50=7e+1nM P00519 30689376 602 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKEL 6npu B 2.33 BS02 KWV B 1 L360 I451 A452 Y454 E481 G482 P484 V487 L103 I179 A180 Y182 E209 G210 P212 V215 D382 A384 R386 N387 D400 P421 D125 A127 R129 N130 D143 P149 2.7.10.2 0004672,0004713,0005524,0006468 ic50=0.00000001M IC50=398nM, EC50=794nM P00519 30689376 605 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKEL