6npe B 2.15 BS01 STI B 1 L267 Y272 K290 E305 M309 I332 T334 F336 M337 I379 H380 A399 D400 F401 L16 Y21 K39 E48 M52 I75 T77 F79 M80 I122 H123 A142 D143 F144 D382 A384 R386 N387 D400 P421 D125 A127 R129 N130 D143 P147 2.7.10.2 0004672,0004713,0005524,0006468 IC50=38nM, Kd=44nM, Ki=13nM, EC50=7e+1nM P00519 30689376 603 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELG 6npe B 2.15 BS02 KWD B 1 A356 L359 L360 I451 A452 E481 G482 P484 V487 A99 L102 L103 I177 A178 E207 G208 P210 V213 D382 A384 R386 N387 D400 P421 D125 A127 R129 N130 D143 P147 2.7.10.2 0004672,0004713,0005524,0006468 ic50=0.00000001M IC50=1259nM, EC50=5012nM P00519 30689376 604 DKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELG