6f3m A 1.6 BS05 NAD B 1 K463 Y467 K455 Y459 H61 S84 S89 D139 E164 N189 K194 D198 N199 C203 H323 H382 S390 Q394 H53 S76 S81 D131 E156 N181 K186 D190 N191 C195 H315 H374 S382 Q386 3.13.2.1 0004013,0005737,0005829,0006730,0016787,0033353,0071269 Q9I685 30054521 501 GFTDYKVADITLAAWGRRELIIAESEMPALMGLRRKYAGQQPLKGAKILGCIHMTIQTGVLIETLVALGAEVRWSSCNIFSTQDQAAAAIAAAGIPVFAWKGETEEEYEWCIEQTILKDGQPWDANMVLDDGGDLTEILHKKYPQMLERIHGITEETTTGVHRLLDMLKNGTLKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSSQSLRQEGMIVKVAEVDPICAMQACMDGFEVVSPYKNGINDGTEASIDAALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGKDGFDAHNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIHLFEQKYADLPAAEKAKRLSVEVLPKKLDEEVALEMVKGFGGVVTQLTPKQAEYIGVSVEGPFKPDTYRY 6f3m B 1.6 BS01 NAD A 1 K463 Y467 K454 Y458 H61 S84 S89 D139 E164 N189 K194 D198 N199 C203 H323 H382 S390 Q394 H52 S75 S80 D130 E155 N180 K185 D189 N190 C194 H314 H373 S381 Q385 3.13.2.1 0004013,0005737,0005829,0006730,0016787,0033353,0071269 Q9I685 30054521 501 FTDYKVADITLAAWGRRELIIAESEMPALMGLRRKYAGQQPLKGAKILGCIHMTIQTGVLIETLVALGAEVRWSSCNIFSTQDQAAAAIAAAGIPVFAWKGETEEEYEWCIEQTILKDGQPWDANMVLDDGGDLTEILHKKYPQMLERIHGITEETTTGVHRLLDMLKNGTLKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSSQSLRQEGMIVKVAEVDPICAMQACMDGFEVVSPYKNGINDGTEASIDAALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGKDGFDAHNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIHLFEQKYADLPAAEKAKRLSVEVLPKKLDEEVALEMVKGFGGVVTQLTPKQAEYIGVSVEGPFKPDTYRY 6f3m B 1.6 BS02 NAD B 1 T165 T166 T167 N199 I227 G230 D231 V232 E251 V252 T298 N300 I321 G322 H323 N375 H382 T156 T157 T158 N190 I218 G221 D222 V223 E242 V243 T289 N291 I312 G313 H314 N366 H373 H61 S84 S89 D139 E164 N189 K194 D198 N199 C203 H323 H382 S390 Q394 H52 S75 S80 D130 E155 N180 K185 D189 N190 C194 H314 H373 S381 Q385 3.13.2.1 0004013,0005737,0005829,0006730,0016787,0033353,0071269 Q9I685 30054521 501 FTDYKVADITLAAWGRRELIIAESEMPALMGLRRKYAGQQPLKGAKILGCIHMTIQTGVLIETLVALGAEVRWSSCNIFSTQDQAAAAIAAAGIPVFAWKGETEEEYEWCIEQTILKDGQPWDANMVLDDGGDLTEILHKKYPQMLERIHGITEETTTGVHRLLDMLKNGTLKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSSQSLRQEGMIVKVAEVDPICAMQACMDGFEVVSPYKNGINDGTEASIDAALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGKDGFDAHNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIHLFEQKYADLPAAEKAKRLSVEVLPKKLDEEVALEMVKGFGGVVTQLTPKQAEYIGVSVEGPFKPDTYRY 6f3m B 1.6 BS03 ADN B 1 H61 T63 Q65 D139 E164 T165 K194 D198 H323 H382 M387 H52 T54 Q56 D130 E155 T156 K185 D189 H314 H373 M378 H61 S84 S89 D139 E164 N189 K194 D198 N199 C203 H323 H382 S390 Q394 H52 S75 S80 D130 E155 N180 K185 D189 N190 C194 H314 H373 S381 Q385 3.13.2.1 0004013,0005737,0005829,0006730,0016787,0033353,0071269 Kd=1.2uM Q9I685 30054521 502 FTDYKVADITLAAWGRRELIIAESEMPALMGLRRKYAGQQPLKGAKILGCIHMTIQTGVLIETLVALGAEVRWSSCNIFSTQDQAAAAIAAAGIPVFAWKGETEEEYEWCIEQTILKDGQPWDANMVLDDGGDLTEILHKKYPQMLERIHGITEETTTGVHRLLDMLKNGTLKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSSQSLRQEGMIVKVAEVDPICAMQACMDGFEVVSPYKNGINDGTEASIDAALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGKDGFDAHNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIHLFEQKYADLPAAEKAKRLSVEVLPKKLDEEVALEMVKGFGGVVTQLTPKQAEYIGVSVEGPFKPDTYRY 6f3m B 1.6 BS04 K B 1 Q65 T380 G381 H382 P383 Q56 T371 G372 H373 P374 H61 S84 S89 D139 E164 N189 K194 D198 N199 C203 H323 H382 S390 Q394 H52 S75 S80 D130 E155 N180 K185 D189 N190 C194 H314 H373 S381 Q385 3.13.2.1 0004013,0005737,0005829,0006730,0016787,0033353,0071269 Q9I685 30054521 504 FTDYKVADITLAAWGRRELIIAESEMPALMGLRRKYAGQQPLKGAKILGCIHMTIQTGVLIETLVALGAEVRWSSCNIFSTQDQAAAAIAAAGIPVFAWKGETEEEYEWCIEQTILKDGQPWDANMVLDDGGDLTEILHKKYPQMLERIHGITEETTTGVHRLLDMLKNGTLKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSSQSLRQEGMIVKVAEVDPICAMQACMDGFEVVSPYKNGINDGTEASIDAALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGKDGFDAHNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIHLFEQKYADLPAAEKAKRLSVEVLPKKLDEEVALEMVKGFGGVVTQLTPKQAEYIGVSVEGPFKPDTYRY 6f3m B 1.6 BS05 ZN B 1 C85 D139 H323 C76 D130 H314 H61 S84 S89 D139 E164 N189 K194 D198 N199 C203 H323 H382 S390 Q394 H52 S75 S80 D130 E155 N180 K185 D189 N190 C194 H314 H373 S381 Q385 3.13.2.1 0004013,0005737,0005829,0006730,0016787,0033353,0071269 Q9I685 30054521 505 FTDYKVADITLAAWGRRELIIAESEMPALMGLRRKYAGQQPLKGAKILGCIHMTIQTGVLIETLVALGAEVRWSSCNIFSTQDQAAAAIAAAGIPVFAWKGETEEEYEWCIEQTILKDGQPWDANMVLDDGGDLTEILHKKYPQMLERIHGITEETTTGVHRLLDMLKNGTLKVPAINVNDSVTKSKNDNKYGCRHSLNDAIKRGTDHLLSGKQALVIGYGDVGKGSSQSLRQEGMIVKVAEVDPICAMQACMDGFEVVSPYKNGINDGTEASIDAALLGKIDLIVTTTGNVNVCDANMLKALKKRAVVCNIGHFDNEIDTAFMRKNWAWEEVKPQVHKIHRTGKDGFDAHNDDYLILLAEGRLVNLGNATGHPSRIMDGSFANQVLAQIHLFEQKYADLPAAEKAKRLSVEVLPKKLDEEVALEMVKGFGGVVTQLTPKQAEYIGVSVEGPFKPDTYRY