5uwm B 1.62 BS01 peptide D 0 Y176 A186 H187 A188 F189 H222 E223 H226 H232 Y66 A76 H77 A78 F79 H112 E113 H116 H122 H222 E223 H226 H232 H112 E113 H116 H122 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 212 ~ 215 LKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYFMLPDDDVQGIQSLYGPG 5uwm B 1.62 BS02 8OA A 1 F241 P242 F131 P132 H222 E223 H226 H232 H112 E113 H116 H122 3.4.24.- 0004222,0006508,0008237,0008270,0031012 ic50=356nM IC50=356nM P45452 28653849 306 LKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYFMLPDDDVQGIQSLYGPG 5uwm B 1.62 BS03 ZN B 1 H222 H226 H232 H112 H116 H122 H222 E223 H226 H232 H112 E113 H116 H122 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 301 LKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYFMLPDDDVQGIQSLYGPG 5uwm B 1.62 BS04 ZN B 2 H172 D174 H187 H200 H62 D64 H77 H90 H222 E223 H226 H232 H112 E113 H116 H122 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 302 LKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYFMLPDDDVQGIQSLYGPG 5uwm B 1.62 BS05 CA B 1 D179 G180 S182 L184 D202 E205 D69 G70 S72 L74 D92 E95 H222 E223 H226 H232 H112 E113 H116 H122 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 303 LKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYFMLPDDDVQGIQSLYGPG 5uwm B 1.62 BS06 CA B 2 D128 D203 E205 D18 D93 E95 H222 E223 H226 H232 H112 E113 H116 H122 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 304 LKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYFMLPDDDVQGIQSLYGPG 5uwm B 1.62 BS07 CA B 3 D162 N194 G196 D198 D52 N84 G86 D88 H222 E223 H226 H232 H112 E113 H116 H122 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 305 LKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYFMLPDDDVQGIQSLYGPG 5uwm B 1.62 BS08 8OA B 1 L184 L185 H222 E223 L239 F241 P242 I243 Y244 T245 L74 L75 H112 E113 L129 F131 P132 I133 Y134 T135 H222 E223 H226 H232 H112 E113 H116 H122 3.4.24.- 0004222,0006508,0008237,0008270,0031012 ic50=356nM IC50=356nM P45452 28653849 306 LKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYFMLPDDDVQGIQSLYGPG