5ue4 B 1.8 BS01 ZN B 1 C99 H226 H230 H236 C53 H177 H181 H187 H226 E227 H230 H236 H177 E178 H181 H187 3.4.24.35 0004222,0006508,0008237,0008270,0031012 P14780 28860188 301 DRQLAEEYLYRYGYTRVAESLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYG 5ue4 B 1.8 BS02 ZN B 2 H175 D177 H190 H203 H126 D128 H141 H154 H226 E227 H230 H236 H177 E178 H181 H187 3.4.24.35 0004222,0006508,0008237,0008270,0031012 P14780 28860188 302 DRQLAEEYLYRYGYTRVAESLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYG 5ue4 B 1.8 BS03 CA B 1 D182 G183 D185 L187 D205 E208 D133 G134 D136 L138 D156 E159 H226 E227 H230 H236 H177 E178 H181 H187 3.4.24.35 0004222,0006508,0008237,0008270,0031012 P14780 28860188 303 DRQLAEEYLYRYGYTRVAESLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYG 5ue4 B 1.8 BS04 CA B 2 D165 G197 Q199 D201 D116 G148 Q150 D152 H226 E227 H230 H236 H177 E178 H181 H187 3.4.24.35 0004222,0006508,0008237,0008270,0031012 P14780 28860188 304 DRQLAEEYLYRYGYTRVAESLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYG 5ue4 B 1.8 BS05 5XQ B 1 V101 P102 R106 F110 L114 Y179 H190 A191 F192 P193 H230 G233 L234 V55 P56 R60 F61 L65 Y130 H141 A142 F143 P144 H181 G184 L185 H226 E227 H230 H236 H177 E178 H181 H187 3.4.24.35 0004222,0006508,0008237,0008270,0031012 Kd=3.3uM -logKd/Ki=6.36, IC50=440nM P14780 28860188 307 DRQLAEEYLYRYGYTRVAESLGPALLLLQKQLSLPETGELDSATLKAMRTPRCGVPDLGRFEGDLKWHHHNITYWIQNYSEDLPRAVIDDAFARAFALWSAVTPLTFTRVYSRDADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGPGIQGDAHFDDDELWSLGKGQGYSLFLVAAHEFGHALGLDHSSVPEALMYPMYRFTEGPPLHKDDVNGIRHLYG