5i0l A 2.45 BS07 H27 B 1 P232 K233 P127 K128 H218 E219 H222 H228 H113 E114 H117 H123 3.4.24.65 0004222,0006508,0008237,0008270,0031012 ic50=18nM -logKd/Ki=7.74, IC50=18nM P39900 27356908 301 GPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 5i0l B 2.45 BS01 H27 B 1 G179 I180 A182 L214 T215 H218 E219 H222 F237 P238 T239 Y240 G75 I76 A78 L110 T111 H114 E115 H118 F133 P134 T135 Y136 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 ic50=18nM P39900 27356908 301 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 5i0l B 2.45 BS02 ZN B 1 H218 H222 H228 H114 H118 H124 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 27356908 302 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 5i0l B 2.45 BS03 ZN B 2 H168 D170 H183 H196 H64 D66 H79 H92 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 27356908 303 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 5i0l B 2.45 BS04 CA B 1 D158 G190 I191 G192 D194 D54 G86 I87 G88 D90 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 27356908 304 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 5i0l B 2.45 BS05 CA B 2 D124 E199 E201 D20 E95 E97 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 27356908 305 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 5i0l B 2.45 BS06 CA B 3 D175 G176 G178 I180 D198 E201 D71 G72 G74 I76 D94 E97 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 27356908 306 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG