3wv1 B 1.98 BS01 ZN B 1 H222 H226 H232 H117 H121 H127 H222 E223 H226 H232 H117 E118 H121 H127 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 25264600 301 YNVFTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 3wv1 B 1.98 BS02 ZN B 2 H172 D174 H187 H200 H67 D69 H82 H95 H222 E223 H226 H232 H117 E118 H121 H127 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 25264600 302 YNVFTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 3wv1 B 1.98 BS03 CA B 1 D179 G180 S182 L184 D202 E205 D74 G75 S77 L79 D97 E100 H222 E223 H226 H232 H117 E118 H121 H127 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 25264600 303 YNVFTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 3wv1 B 1.98 BS04 CA B 2 D162 N194 G196 D198 D57 N89 G91 D93 H222 E223 H226 H232 H117 E118 H121 H127 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 25264600 304 YNVFTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 3wv1 B 1.98 BS05 NA B 1 D128 D203 E205 T206 D23 D98 E100 T101 H222 E223 H226 H232 H117 E118 H121 H127 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 25264600 305 YNVFTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 3wv1 B 1.98 BS06 WHH B 1 K140 N215 F217 L218 H222 L239 F241 I243 Y244 T245 T247 K249 F252 M253 P255 K35 N110 F112 L113 H117 L134 F136 I138 Y139 T140 T142 K144 F147 M148 P150 H222 E223 H226 H232 H117 E118 H121 H127 3.4.24.- 0004222,0006508,0008237,0008270,0031012 ic50=0.0039nM IC50=0.003900nM P45452 25264600 307 YNVFTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG