3sls B 2.3 BS01 ANP B 1 L74 G75 A76 G80 V82 A95 K97 M143 M146 S150 Q153 D190 K192 S194 N195 L197 D208 L33 G34 A35 G39 V41 A54 K56 M102 M105 S109 Q112 D149 K151 S153 N154 L156 D167 D190 K192 S194 N195 D208 D217 T226 D149 K151 S153 N154 D167 D176 T180 2.7.12.2 0004672,0005524,0006468 Q02750 22245778 400 MTLQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDFVGTRSYMSPERLQGTYSVQSDIWSMGLSLVEMAVGRYPIGSMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQ 3sls B 2.3 BS02 MG B 1 N195 D208 N154 D167 D190 K192 S194 N195 D208 D217 T226 D149 K151 S153 N154 D167 D176 T180 2.7.12.2 0004672,0005524,0006468 Q02750 22245778 401 MTLQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDFVGTRSYMSPERLQGTYSVQSDIWSMGLSLVEMAVGRYPIGSMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQ 3sls B 2.3 BS03 77D B 1 N78 K97 V127 I141 M143 D208 F209 G210 V211 S212 N37 K56 V86 I100 M102 D167 F168 G169 V170 S171 D190 K192 S194 N195 D208 D217 T226 D149 K151 S153 N154 D167 D176 T180 2.7.12.2 0004672,0005524,0006468 IC50=22nM Q02750 22245778 500 MTLQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQIIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGRIPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDFVGTRSYMSPERLQGTYSVQSDIWSMGLSLVEMAVGRYPIGSMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAFIKRSDAEEVDFAGWLCSTIGLNQ