3pz1 B 1.95 BS01 3PZ B 1 Y44 W52 D238 W244 F289 H290 Y37 W45 D231 W237 F282 H283 H190 R232 K235 D238 C240 Y241 D280 D287 H290 H183 R225 K228 D231 C233 Y234 D273 D280 H283 2.5.1.60 0003824,0004659,0004661,0004663,0005515,0005968,0008270,0008318,0018344,0019840,0031267,0046872 ic50=724nM -logKd/Ki=6.14, IC50=724nM Q08603 21520375 1 QKDVTIKSDAPDTLLLEKHADYIASYGSDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS 3pz1 B 1.95 BS02 ZN B 1 D238 C240 H290 D231 C233 H283 H190 R232 K235 D238 C240 Y241 D280 D287 H290 H183 R225 K228 D231 C233 Y234 D273 D280 H283 2.5.1.60 0003824,0004659,0004661,0004663,0005515,0005968,0008270,0008318,0018344,0019840,0031267,0046872 Q08603 21520375 332 QKDVTIKSDAPDTLLLEKHADYIASYGSDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS 3pz1 B 1.95 BS03 CA B 1 H64 M66 H57 M59 H190 R232 K235 D238 C240 Y241 D280 D287 H290 H183 R225 K228 D231 C233 Y234 D273 D280 H283 2.5.1.60 0003824,0004659,0004661,0004663,0005515,0005968,0008270,0008318,0018344,0019840,0031267,0046872 Q08603 21520375 333 QKDVTIKSDAPDTLLLEKHADYIASYGSDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNKEEILVFIKSCQHECGGVSASIGHDPHLLYTLSAVQILTLYDSIHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS