3kcf B 2.8 BS01 JZO B 1 A230 K232 Y249 L260 S280 Y282 H283 L340 A60 K62 Y79 L90 S110 Y112 H113 L166 D333 K335 N338 D351 T375 D159 K161 N164 D177 T198 2.7.11.30 0004672,0004675,0005524,0006468,0007178,0016020 IC50=3690nM, Ki=35nM P36897 19914068 2 ISEGTTLKDLIYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALSTASGLAHLHMEIGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIKKTLSQLSQQEGI