3e88 B 2.5 BS01 peptide D 0 E193 E236 F238 D275 K277 E279 T309 F310 C311 G312 T313 E315 E342 L348 E48 E91 F93 D130 K132 E134 T164 F165 C166 G167 T168 E170 E197 L203 D275 K277 N280 D293 T313 D130 K132 N135 D148 T168 2.7.11.1 0004672,0004674,0005524,0006468 P31751 19179070 3 ~ 12 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITQRTHFPQFDYSASIR 3e88 B 2.5 BS02 G96 B 1 G159 G164 K165 V166 A179 K181 E200 L204 F227 M229 M282 T292 D293 F294 F439 G14 G19 K20 V21 A34 K36 E55 L59 F82 M84 M137 T147 D148 F149 F294 D275 K277 N280 D293 T313 D130 K132 N135 D148 T168 2.7.11.1 0004672,0004674,0005524,0006468 Ki=2nM Ki=2nM, IC50=10nM P31751 19179070 1 KVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIVSALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDDEFTAQSITITQRTHFPQFDYSASIR