3ce6 A 1.6 BS03 NAD B 1 K489 Y493 K480 Y484 H69 S92 S97 D156 E218 N243 K248 D252 N253 T257 H363 H416 S424 Q428 H60 S83 S88 D147 E209 N234 K239 D243 N244 T248 H354 H407 S415 Q419 3.13.2.1 0004013,0005515,0005576,0005737,0005829,0005886,0006730,0009087,0009274,0016787,0033353,0035375,0035635,0044650,0046085,0070403,0071269 P9WGV3 18815415 550 SLTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 3ce6 B 1.6 BS01 NAD A 1 K489 Y493 K479 Y483 H69 S92 S97 D156 E218 N243 K248 D252 N253 T257 H363 H416 S424 Q428 H59 S82 S87 D146 E208 N233 K238 D242 N243 T247 H353 H406 S414 Q418 3.13.2.1 0004013,0005515,0005576,0005737,0005829,0005886,0006730,0009087,0009274,0016787,0033353,0035375,0035635,0044650,0046085,0070403,0071269 P9WGV3 18815415 550 LTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 3ce6 B 1.6 BS02 ADN B 1 H69 T71 Q73 D156 E218 T219 D252 H363 L410 G415 H416 M421 H59 T61 Q63 D146 E208 T209 D242 H353 L400 G405 H406 M411 H69 S92 S97 D156 E218 N243 K248 D252 N253 T257 H363 H416 S424 Q428 H59 S82 S87 D146 E208 N233 K238 D242 N243 T247 H353 H406 S414 Q418 3.13.2.1 0004013,0005515,0005576,0005737,0005829,0005886,0006730,0009087,0009274,0016787,0033353,0035375,0035635,0044650,0046085,0070403,0071269 ic50~500uM P9WGV3 18815415 500 LTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY 3ce6 B 1.6 BS03 NAD B 1 T219 T220 T221 N253 G284 D285 V286 T304 E305 I306 N310 T338 G339 N340 I343 I361 G362 H363 N409 H416 T209 T210 T211 N243 G274 D275 V276 T294 E295 I296 N300 T328 G329 N330 I333 I351 G352 H353 N399 H406 H69 S92 S97 D156 E218 N243 K248 D252 N253 T257 H363 H416 S424 Q428 H59 S82 S87 D146 E208 N233 K238 D242 N243 T247 H353 H406 S414 Q418 3.13.2.1 0004013,0005515,0005576,0005737,0005829,0005886,0006730,0009087,0009274,0016787,0033353,0035375,0035635,0044650,0046085,0070403,0071269 P9WGV3 18815415 550 LTPDVRNGIDFKIADLSLADFGRKELRIAEHEMPGLMSLRREYAEVQPLKGARISGSLHMTVQTAVLIETLTALGAEVRWASCNIFSTQDHAAAAVVVGPHGTPDEPKGVPVFAWKGETLEEYWWAAEQMLTWPDPDKPANMILDDGGDATMLVLRGMQYEKAGVVPPAEEDDPAEWKVFLNLLRTRFETDKDKWTKIAESVKGVTEETTTGVLRLYQFAAAGDLAFPAINVNDSVTKSKFDNKYGTRHSLIDGINRGTDALIGGKKVLICGYGDVGKGCAEAMKGQGARVSVTEIDPINALQAMMEGFDVVTVEEAIGDADIVVTATGNKDIIMLEHIKAMKDHAILGNIGHFDNEIDMAGLERSGATRVNVKPQVDLWTFGDTGRSIIVLSEGRLLNLGNATGHPSFVMSNSFANQTIAQIELWTKNDEYDNEVYRLPKHLDEKVARIHVEALGGHLTKLTKEQAEYLGVDVEGPYKPDHYRY