2piy B 1.43 BS01 ZN B 1 H69 E72 H196 H64 E67 H192 H69 E72 R127 H196 E270 H64 E67 R122 H192 E266 3.4.17.2 0004181,0006508,0008270 P09955 18219114 500 GHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL 2piy B 1.43 BS02 528 B 1 H69 E72 R127 N144 R145 T164 H196 Y198 L203 S207 Y248 D255 E270 H64 E67 R122 N139 R140 T159 H192 Y194 L199 S203 Y244 D251 E266 H69 E72 R127 H196 E270 H64 E67 R122 H192 E266 3.4.17.2 0004181,0006508,0008270 ic50=20nM P09955 18219114 501 GHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGKPGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLDFYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTTGASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMILYPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGGSDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNYVLGHL