2p53 B 2.1 BS01 ZN B 1 E131 H195 H216 E131 H195 H216 3.5.1.25 0006040,0006044,0006046,0008270,0008448,0016787,0016810,0019262,0032991,0042802,0046872,0047419,0051289 P0AF18 17567048 401 MYALTQGRIFTGHEFLDDHAVVIADGLIKSVCPVAELPPEIEQRSLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNYLPTLITTSDELMKQGVRVMREYLAKHPNQALGLHLEGPWLNLVKKGTHNPNFVRKPDAALVDFLCENADVITKVTLAPEMVPAEVISKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLYNAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRNAKRLKGDKLCLVTNATAPAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRMATLYPARAIGVEKRLGTLAAGKVANLTAFTPDFKITKTIVNGNEVVTQ 2p53 B 2.1 BS02 NNG B 1 N61 E131 G141 T142 H143 H195 H216 N219 A220 H251 N273 F287 L306 G308 N61 E131 G141 T142 H143 H195 H216 N219 A220 H251 N273 F287 L306 G308 3.5.1.25 0006040,0006044,0006046,0008270,0008448,0016787,0016810,0019262,0032991,0042802,0046872,0047419,0051289 -logKd/Ki=7.46, Ki=35nM P0AF18 17567048 411 MYALTQGRIFTGHEFLDDHAVVIADGLIKSVCPVAELPPEIEQRSLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNYLPTLITTSDELMKQGVRVMREYLAKHPNQALGLHLEGPWLNLVKKGTHNPNFVRKPDAALVDFLCENADVITKVTLAPEMVPAEVISKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLYNAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRNAKRLKGDKLCLVTNATAPAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRMATLYPARAIGVEKRLGTLAAGKVANLTAFTPDFKITKTIVNGNEVVTQ