1lpz B 2.4 BS01 CA B 1 D70 N72 Q75 E80 D56 N58 Q61 E66 H57 D102 Q192 G193 D194 S195 G196 H42 D88 Q182 G183 D184 S185 G186 3.4.21.6 0004252,0006508 P00742 12061878 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT 1lpz B 2.4 BS02 CMB B 1 T98 Y99 R143 D189 A190 C191 Q192 W215 G216 G219 C220 T84 Y85 R132 D179 A180 C181 Q182 W205 G206 G208 C209 H57 D102 Q192 G193 D194 S195 G196 H42 D88 Q182 G183 D184 S185 G186 3.4.21.6 0004252,0006508 Ki=25nM -logKd/Ki=7.60, Ki=25nM Ki=25nM P00742 12061878 301 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT