1kvo B 2.0 BS01 CA B 1 H27 G29 G31 D48 H27 G29 G31 D48 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 P14555 8831753 191 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 1kvo B 2.0 BS02 CA B 2 F23 G25 Y112 N114 F23 G25 Y112 N114 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 P14555 8831753 192 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC 1kvo B 2.0 BS03 OAP B 1 L2 F5 A17 A18 Y21 G29 V30 G31 C44 H47 D48 Y51 L2 F5 A17 A18 Y21 G29 V30 G31 C44 H47 D48 Y51 H27 G29 G31 H47 D48 Y51 Y66 D91 H27 G29 G31 H47 D48 Y51 Y66 D91 3.1.1.4 0004623,0005509,0005543,0005576,0005615,0005739,0005741,0005783,0005789,0005886,0006629,0006644,0006954,0010744,0016042,0016787,0030141,0031640,0034374,0036335,0042130,0042742,0046337,0046470,0046473,0046872,0047498,0048471,0050482,0050729,0050830,0070062,0070374,1902563 ic50=0.013uM IC50=21nM P14555 8831753 190 NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC