6wvo A 2.19 BS01 GD8 A 1 W86 G120 G121 G122 S203 A204 F295 Y337 H447 W83 G117 G118 G119 S200 A201 F286 Y328 H438 G121 G122 G154 S203 A204 G242 F297 F299 E334 H447 G118 G119 G151 S200 A201 G239 F288 F290 E325 H438 3.1.1.7 0001507,0001540,0001919,0002076,0003990,0004104,0005515,0005518,0005576,0005604,0005615,0005634,0005794,0005886,0006581,0007155,0007399,0007416,0009986,0016020,0016787,0017171,0031594,0031623,0032223,0042166,0042802,0042803,0042982,0043083,0043236,0045202,0048471,0050714,0052689,0060041,0095500,0098552,0120162 P22303 33538594 603 EDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA 6wvo A 2.19 BS02 HI6 A 1 Y72 Y124 V282 E285 W286 V294 F295 Y337 Y341 Y69 Y121 V273 E276 W277 V285 F286 Y328 Y332 G121 G122 G154 S203 A204 G242 F297 F299 E334 H447 G118 G119 G151 S200 A201 G239 F288 F290 E325 H438 3.1.1.7 0001507,0001540,0001919,0002076,0003990,0004104,0005515,0005518,0005576,0005604,0005615,0005634,0005794,0005886,0006581,0007155,0007399,0007416,0009986,0016020,0016787,0017171,0031594,0031623,0032223,0042166,0042802,0042803,0042982,0043083,0043236,0045202,0048471,0050714,0052689,0060041,0095500,0098552,0120162 IC50=667800nM, Kd=93000nM P22303 33538594 604 EDAELLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQSVCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARRRATQLAHLVGCPNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVGVPQVSDLAAEAVVLHYTDWLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFARTGDPNEPPKAPQWPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRFLPKLLSA