6w13 A 2.38 BS01 dna B 0 N149 P244 G245 V246 G247 T248 K249 V250 D268 V269 N138 P233 G234 V235 G236 T237 K238 V239 D257 V258 K249 D268 K238 D257 3.2.2.-,4.2.99.18 0000978,0003677,0003684,0003824,0004519,0005515,0005634,0005654,0005739,0005759,0005829,0006281,0006284,0006285,0006289,0006355,0006974,0006979,0008017,0008534,0009314,0009410,0009416,0016363,0016607,0016798,0016829,0019104,0019899,0032355,0032357,0032991,0034039,0034614,0043066,0044029,0045007,0045008,0045471,0045944,0051593,0071276,0140078,0140097,1901291 O15527 32895378 21 ~ 27 GSEGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQQVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARCVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADWICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLR 6w13 A 2.38 BS02 dna C 0 N149 R154 Y203 N138 R143 Y192 K249 D268 K238 D257 3.2.2.-,4.2.99.18 0000978,0003677,0003684,0003824,0004519,0005515,0005634,0005654,0005739,0005759,0005829,0006281,0006284,0006285,0006289,0006355,0006974,0006979,0008017,0008534,0009314,0009410,0009416,0016363,0016607,0016798,0016829,0019104,0019899,0032355,0032357,0032991,0034039,0034614,0043066,0044029,0045007,0045008,0045471,0045944,0051593,0071276,0140078,0140097,1901291 O15527 32895378 5 ~ 10 GSEGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQQVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARCVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADWICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLR 6w13 A 2.38 BS03 MG A 1 Q135 S143 Q124 S132 K249 D268 K238 D257 3.2.2.-,4.2.99.18 0000978,0003677,0003684,0003824,0004519,0005515,0005634,0005654,0005739,0005759,0005829,0006281,0006284,0006285,0006289,0006355,0006974,0006979,0008017,0008534,0009314,0009410,0009416,0016363,0016607,0016798,0016829,0019104,0019899,0032355,0032357,0032991,0034039,0034614,0043066,0044029,0045007,0045008,0045471,0045944,0051593,0071276,0140078,0140097,1901291 O15527 32895378 401 GSEGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQQVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARCVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADWICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLR 6w13 A 2.38 BS04 MG A 2 C241 L243 V246 C230 L232 V235 K249 D268 K238 D257 3.2.2.-,4.2.99.18 0000978,0003677,0003684,0003824,0004519,0005515,0005634,0005654,0005739,0005759,0005829,0006281,0006284,0006285,0006289,0006355,0006974,0006979,0008017,0008534,0009314,0009410,0009416,0016363,0016607,0016798,0016829,0019104,0019899,0032355,0032357,0032991,0034039,0034614,0043066,0044029,0045007,0045008,0045471,0045944,0051593,0071276,0140078,0140097,1901291 O15527 32895378 402 GSEGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQQVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARCVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADWICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLR 6w13 A 2.38 BS05 MG A 3 W307 G308 P309 Y310 W296 G297 P298 Y299 K249 D268 K238 D257 3.2.2.-,4.2.99.18 0000978,0003677,0003684,0003824,0004519,0005515,0005634,0005654,0005739,0005759,0005829,0006281,0006284,0006285,0006289,0006355,0006974,0006979,0008017,0008534,0009314,0009410,0009416,0016363,0016607,0016798,0016829,0019104,0019899,0032355,0032357,0032991,0034039,0034614,0043066,0044029,0045007,0045008,0045471,0045944,0051593,0071276,0140078,0140097,1901291 O15527 32895378 403 GSEGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQQVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARCVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADWICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLR 6w13 A 2.38 BS06 MG A 4 L187 A188 G189 S209 R213 L176 A177 G178 S198 R202 K249 D268 K238 D257 3.2.2.-,4.2.99.18 0000978,0003677,0003684,0003824,0004519,0005515,0005634,0005654,0005739,0005759,0005829,0006281,0006284,0006285,0006289,0006355,0006974,0006979,0008017,0008534,0009314,0009410,0009416,0016363,0016607,0016798,0016829,0019104,0019899,0032355,0032357,0032991,0034039,0034614,0043066,0044029,0045007,0045008,0045471,0045944,0051593,0071276,0140078,0140097,1901291 O15527 32895378 404 GSEGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQQVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARCVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADWICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLR 6w13 A 2.38 BS07 S5Y B 1 Y203 C207 Y192 C196 K249 D268 K238 D257 3.2.2.-,4.2.99.18 0000978,0003677,0003684,0003824,0004519,0005515,0005634,0005654,0005739,0005759,0005829,0006281,0006284,0006285,0006289,0006355,0006974,0006979,0008017,0008534,0009314,0009410,0009416,0016363,0016607,0016798,0016829,0019104,0019899,0032355,0032357,0032991,0034039,0034614,0043066,0044029,0045007,0045008,0045471,0045944,0051593,0071276,0140078,0140097,1901291 O15527 32895378 101 GSEGHRTLASTPALWASIPCPRSELRLDLVLPSGQSFRWREQSPAHWSGVLADQVWTLTQTEEQLHCTVYRSQASRPTPDELEAVRKYFQLDVTLAQLYHHWGSVDSHFQQVAQKFQGVRLLRQDPIECLFSFICSSNNNIARITGMVERLCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEAHLRKLGLGYRARCVSASARAILEEQGGLAWLQQLRESSYEEAHKALCILPGVGTKVADWICLMALDKPQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQTNKELGNFFRSLWGPYAGWAQAVLFSADLR