6hd4 A 2.03 BS01 FYW A 1 A356 L359 L360 A452 T453 Y454 E481 P484 V487 I521 V525 A114 L117 L118 A210 T211 Y212 E239 P242 V245 I279 V283 D382 A384 R386 N387 D400 P421 D140 A142 R144 N145 D158 P179 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=8.64, IC50=0.0023uM P00520 30137981 603 GAMDPSSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKEL 6hd4 A 2.03 BS02 STI A 1 Y272 V275 A288 K290 E305 M309 I312 V318 I332 T334 F336 M337 I379 H380 L389 A399 D400 F401 Y31 V34 A47 K49 E63 M67 I70 V76 I90 T92 F94 M95 I137 H138 L147 A157 D158 F159 D382 A384 R386 N387 D400 P421 D140 A142 R144 N145 D158 P179 2.7.10.2 0004672,0004713,0005524,0006468 IC50=10.8nM P00520 30137981 604 GAMDPSSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVSAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKEL