6ekn A 1.2 BS01 ZN A 1 H218 H222 H228 H114 H118 H124 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 29727184 301 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 6ekn A 1.2 BS02 ZN A 2 H168 D170 H183 H196 H64 D66 H79 H92 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 29727184 302 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 6ekn A 1.2 BS03 CA A 1 D158 G190 G192 D194 D54 G86 G88 D90 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 29727184 303 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 6ekn A 1.2 BS04 CA A 2 D124 E199 E201 D20 E95 E97 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 29727184 304 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 6ekn A 1.2 BS05 CA A 3 D175 G176 G178 I180 D198 E201 D71 G72 G74 I76 D94 E97 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 P39900 29727184 305 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG 6ekn A 1.2 BS06 B9N A 1 I180 L181 A182 H183 H218 E219 H222 H228 V235 P238 T239 Y240 I76 L77 A78 H79 H114 E115 H118 H124 V131 P134 T135 Y136 H218 E219 H222 H228 H114 E115 H118 H124 3.4.24.65 0004222,0006508,0008237,0008270,0031012 -logKd/Ki=6.29, IC50=510nM IC50=510nM P39900 29727184 306 MGPVWRKHYITYRINNYTPDMNREDVDYAIRKAFQVWSNVTPLKFSKINTGMADILVVFARGAHGDDHAFDGKGGILAHAFGPGSGIGGDAHFDEDEFWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTYKYVDINTFRLSADDIRGIQSLYG