6duk A 2.2 BS01 MG A 1 N842 D855 N142 D155 D837 A839 R841 N842 D855 D137 A139 R141 N142 D155 2.7.10.1 0004672,0004713,0005524,0006468 P00533 31092401 1101 QALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEED 6duk A 2.2 BS02 ANP A 1 S720 G721 A722 V726 A743 K745 M790 L792 M793 C797 D837 R841 N842 L844 S20 G21 A22 V26 A43 K45 M90 L92 M93 C97 D137 R141 N142 L144 D837 A839 R841 N842 D855 D137 A139 R141 N142 D155 2.7.10.1 0004672,0004713,0005524,0006468 P00533 31092401 1102 QALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEED 6duk A 2.2 BS03 JBJ A 1 F723 A743 K745 L747 E749 I759 M766 C775 R776 L777 L788 M790 D855 F856 L858 L861 L862 E865 F23 A43 K45 L47 E49 I59 M66 C75 R76 L77 L88 M90 D155 F156 L158 L161 L162 E165 D837 A839 R841 N842 D855 D137 A139 R141 N142 D155 2.7.10.1 0004672,0004713,0005524,0006468 -logKd/Ki=9.59, IC50=0.26nM IC50=>1000nM P00533 31092401 1103 QALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEED