6cpw A 1.85 BS01 F8V A 1 I29 A33 Y34 A50 K52 Y62 T66 E69 D104 M106 E107 T108 L154 D165 I12 A16 Y17 A28 K30 Y40 T44 E47 D82 M84 E85 T86 L132 D143 D147 K149 N152 D165 T188 D125 K127 N130 D143 T166 2.7.11.24 0000165,0001784,0003690,0004672,0004674,0004707,0005515,0005524,0005634,0005654,0005737,0005739,0005769,0005770,0005794,0005813,0005819,0005829,0005856,0005886,0005901,0005925,0006357,0006468,0006915,0006974,0007166,0007507,0008284,0008286,0008353,0009636,0009887,0010759,0014032,0014044,0014069,0015966,0016020,0016301,0016310,0018105,0018107,0019233,0019858,0019901,0019902,0030278,0030335,0030424,0030521,0030641,0030878,0031143,0031435,0031647,0031663,0032212,0032355,0032496,0032839,0032872,0032991,0033574,0033598,0034198,0034614,0035094,0035556,0036120,0038127,0038133,0042220,0042307,0042473,0042542,0042552,0042802,0043204,0043330,0043401,0043627,0044849,0045596,0045727,0045893,0046697,0048009,0048538,0050847,0050852,0050853,0051403,0051493,0060020,0060045,0060291,0060324,0060425,0060440,0060716,0061308,0061431,0070161,0070371,0070849,0071276,0071320,0071356,0071364,0071380,0072584,0072686,0090170,0097237,0097305,0106310,0120041,1904355,1990314,2000641 ic50=5.6nM -logKd/Ki=8.25, Kd=5.6nM P63086 29748051 403 VFDVRYTNLSYIGEGAYGMVCSAYDRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFLDDLPKEKLKELIFEETARFQPG