5zc9 A 2.0 BS01 rna B 0 P108 T109 R110 G136 G137 V140 T158 P159 G160 R161 D164 R168 R190 G191 F192 Q195 N280 T281 R282 H303 G304 R311 T329 D330 L331 P80 T81 R82 G108 G109 V112 T130 P131 G132 R133 D136 R140 R162 G163 F164 Q167 N252 T253 R254 H275 G276 R283 T301 D302 L303 3.6.4.13 0000339,0002183,0003676,0003723,0003724,0003725,0003729,0003743,0004386,0005515,0005524,0005634,0005737,0005829,0005886,0006412,0006413,0008135,0016020,0016281,0016787,0016887,0045944,0048471,0070062,0097165 Kd=7.6uM P60842 30595437 1 ~ 10 EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 5zc9 A 2.0 BS02 ANP A 1 F52 Q59 G79 G81 K82 T83 G335 D337 R362 R365 F366 F24 Q31 G51 G53 K54 T55 G307 D309 R334 R337 F338 3.6.4.13 0000339,0002183,0003676,0003723,0003724,0003725,0003729,0003743,0004386,0005515,0005524,0005634,0005737,0005829,0005886,0006412,0006413,0008135,0016020,0016281,0016787,0016887,0045944,0048471,0070062,0097165 P60842 30595437 500 EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 5zc9 A 2.0 BS03 RCG B 1 F163 Q195 F135 Q167 3.6.4.13 0000339,0002183,0003676,0003723,0003724,0003725,0003729,0003743,0004386,0005515,0005524,0005634,0005737,0005829,0005886,0006412,0006413,0008135,0016020,0016281,0016787,0016887,0045944,0048471,0070062,0097165 IC50=47nM, Kd=156nM P60842 30595437 600 EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI