5wg3 A 2.896 BS01 AFM A 1 R199 G200 F202 G203 V205 K220 E239 M274 D278 A321 L324 D335 R170 G171 F173 G174 V176 K191 E210 M245 D249 A292 L295 D306 D317 K319 N322 D335 K344 T353 D288 K290 N293 D306 K315 T324 2.7.11.15 0001664,0002026,0002029,0003108,0004672,0004674,0004703,0005515,0005524,0005737,0005829,0005886,0005929,0006468,0007165,0007186,0007213,0007217,0007507,0016020,0016310,0018105,0019079,0031623,0031694,0031755,0032473,0033605,0042995,0045202,0045988,0046718,0047696,0060048,0098793,0098794,1901081 -logKd/Ki=8.10, IC50=0.008uM P25098 29070696 701 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRTKDKHEIDRMTLTVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP 5wg3 A 2.896 BS02 MG A 1 H348 E360 V361 Q363 V366 Y368 H319 E331 V332 Q334 V337 Y339 D317 K319 N322 D335 K344 T353 D288 K290 N293 D306 K315 T324 2.7.11.15 0001664,0002026,0002029,0003108,0004672,0004674,0004703,0005515,0005524,0005737,0005829,0005886,0005929,0006468,0007165,0007186,0007213,0007217,0007507,0016020,0016310,0018105,0019079,0031623,0031694,0031755,0032473,0033605,0042995,0045202,0045988,0046718,0047696,0060048,0098793,0098794,1901081 P25098 29070696 702 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRTKDKHEIDRMTLTVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP