5uwl A 2.55 BS01 ZN A 1 H222 H226 H232 H113 H117 H123 H222 E223 H226 H232 H113 E114 H117 H123 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 301 TLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 5uwl A 2.55 BS02 ZN A 2 H172 D174 H187 H200 H63 D65 H78 H91 H222 E223 H226 H232 H113 E114 H117 H123 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 302 TLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 5uwl A 2.55 BS03 CA A 1 D179 G180 S182 L184 D202 E205 D70 G71 S73 L75 D93 E96 H222 E223 H226 H232 H113 E114 H117 H123 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 303 TLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 5uwl A 2.55 BS04 CA A 2 D128 D203 E205 D19 D94 E96 H222 E223 H226 H232 H113 E114 H117 H123 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 304 TLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 5uwl A 2.55 BS05 CA A 3 D162 N194 G196 D198 D53 N85 G87 D89 H222 E223 H226 H232 H113 E114 H117 H123 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 305 TLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG 5uwl A 2.55 BS06 8OJ A 1 G183 L184 L185 Y214 L218 H222 E223 L239 F241 P242 I243 Y244 T245 T247 P255 G74 L75 L76 Y105 L109 H113 E114 L130 F132 P133 I134 Y135 T136 T138 P146 H222 E223 H226 H232 H113 E114 H117 H123 3.4.24.- 0004222,0006508,0008237,0008270,0031012 -logKd/Ki=8.03, IC50=9.4nM IC50=9.4nM P45452 28653849 306 TLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGPG