5uwk A 1.6 BS01 ZN A 1 H222 H226 H232 H116 H120 H126 H222 E223 H226 H232 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 301 FPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGFMLPDDDVQGIQSLYGPG 5uwk A 1.6 BS02 ZN A 2 H172 D174 H187 H200 H66 D68 H81 H94 H222 E223 H226 H232 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 302 FPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGFMLPDDDVQGIQSLYGPG 5uwk A 1.6 BS03 CA A 1 D179 G180 S182 L184 D202 E205 D73 G74 S76 L78 D96 E99 H222 E223 H226 H232 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 303 FPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGFMLPDDDVQGIQSLYGPG 5uwk A 1.6 BS04 CA A 2 D128 D203 E205 D22 D97 E99 H222 E223 H226 H232 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 304 FPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGFMLPDDDVQGIQSLYGPG 5uwk A 1.6 BS05 CA A 3 D162 N194 G196 D198 D56 N88 G90 D92 H222 E223 H226 H232 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 P45452 28653849 305 FPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGFMLPDDDVQGIQSLYGPG 5uwk A 1.6 BS06 8OM A 1 L184 L185 A186 H222 E223 H226 H232 L239 F241 I243 Y244 T245 T247 P255 L78 L79 A80 H116 E117 H120 H126 L133 F135 I137 Y138 T139 T141 P146 H222 E223 H226 H232 H116 E117 H120 H126 3.4.24.- 0004222,0006508,0008237,0008270,0031012 Ki=2.3nM -logKd/Ki=8.64, Ki=2.3nM IC50=2.2nM, Ki=2.3nM P45452 28653849 306 FPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGFMLPDDDVQGIQSLYGPG