5ukm A 3.03 BS01 T0E A 1 I197 R199 G200 F202 G203 E204 V205 A218 E239 V255 M274 A321 L324 S334 D335 I167 R169 G170 F172 G173 E174 V175 A188 E209 V225 M244 A291 L294 S304 D305 D317 K319 N322 D335 K344 T353 D287 K289 N292 D305 K314 T323 2.7.11.15 0001664,0002026,0002029,0002031,0003108,0004672,0004674,0004703,0005515,0005524,0005737,0005829,0005886,0006468,0006886,0007165,0007186,0007213,0009966,0016020,0016310,0018105,0031694,0031755,0042995,0045202,0045880,0045988,0047696,0060048,0098793,0098794,1901081,1903566 -logKd/Ki=7.52, IC50=0.03uM IC50=30nM P21146 28323425 701 KILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKMWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPR 5ukm A 3.03 BS02 MG A 1 H348 Q363 V366 Y368 H318 Q333 V336 Y338 D317 K319 N322 D335 K344 T353 D287 K289 N292 D305 K314 T323 2.7.11.15 0001664,0002026,0002029,0002031,0003108,0004672,0004674,0004703,0005515,0005524,0005737,0005829,0005886,0006468,0006886,0007165,0007186,0007213,0009966,0016020,0016310,0018105,0031694,0031755,0042995,0045202,0045880,0045988,0047696,0060048,0098793,0098794,1901081,1903566 P21146 28323425 702 KILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKMWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKPR