5ukk A 2.6 BS01 MG A 1 H348 E360 V361 Q363 V366 H310 E322 V323 Q325 V328 D317 K319 N322 D335 K344 T353 D279 K281 N284 D297 K306 T315 2.7.11.15 0001664,0002026,0002029,0003108,0004672,0004674,0004703,0005515,0005524,0005737,0005829,0005886,0005929,0006468,0007165,0007186,0007213,0007217,0007507,0016020,0016310,0018105,0019079,0031623,0031694,0031755,0032473,0033605,0042995,0045202,0045988,0046718,0047696,0060048,0098793,0098794,1901081 P25098 28323425 701 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNK 5ukk A 2.6 BS02 8DJ A 1 I197 R199 G200 F202 G203 V205 A218 L222 L235 A236 E239 V255 M274 D278 A321 L324 D335 A480 I159 R161 G162 F164 G165 V167 A180 L184 L197 A198 E201 V217 M236 D240 A283 L286 D297 A442 D317 K319 N322 D335 K344 T353 D279 K281 N284 D297 K306 T315 2.7.11.15 0001664,0002026,0002029,0003108,0004672,0004674,0004703,0005515,0005524,0005737,0005829,0005886,0005929,0006468,0007165,0007186,0007213,0007217,0007507,0016020,0016310,0018105,0019079,0031623,0031694,0031755,0032473,0033605,0042995,0045202,0045988,0046718,0047696,0060048,0098793,0098794,1901081 -logKd/Ki=6.21, IC50=0.61uM P25098 28323425 702 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAADAFDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFILQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNK