5tx3 A 2.9 BS01 7MY A 1 V25 K40 Y88 C89 E93 L139 I149 V25 K40 Y80 C81 E85 L131 I141 D132 K134 E136 N137 D150 S171 D124 K126 E128 N129 D142 S147 2.7.10.2,2.7.11.1 0004672,0004674,0005524,0006468 -logKd/Ki=8.85, IC50~1.4nM Q14680 28926338 1000 SGSMKDYDELLKYYELHETIGTAKVKLACHILTGEMVAIKIMDKNIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLGSLAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR 5tx3 A 2.9 BS02 7MY B 1 E15 T16 E18 T19 D132 K134 E136 N137 D150 S171 D124 K126 E128 N129 D142 S147 2.7.10.2,2.7.11.1 0004672,0004674,0005524,0006468 -logKd/Ki=8.85, IC50~1.4nM Q14680 28926338 1001 SGSMKDYDELLKYYELHETIGTAKVKLACHILTGEMVAIKIMDKNIKTEIEALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVSAVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLGSLAYAAPELIQGKGSEADVWSMGILLYVLMCGFLPFDDDNVMALYKKIMRGKYDVPKWLSPSSILLLQQMLQVDPKKRISMKNLLNHPWIMQDYNYPVEWQSKNPFIHLDDDCVTELSVHHRNNRQTMEDLISLWQYDHLTATYLLLLAKKARGKPVRLR