5tr6 A 1.93 BS01 7KG A 1 A400 E449 M450 A451 G454 P455 R498 L501 S511 D512 A39 E82 M83 A84 G87 P88 R131 L134 S144 D145 D494 A496 R498 N499 D512 K533 D127 A129 R131 N132 D145 K166 2.7.10.2 0004672,0004713,0005524,0006468 ic50=3.2nM -logKd/Ki=8.49, IC50=3.2nM IC50=2.0nM, EC50=9.8nM P43405 27839918 701 EVYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILPALKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYDVENRPGFAAVELRLRNYYYDVVNHHHH