5tf9 A 2.5 BS01 7AV A 1 L252 F265 E268 V281 F283 L299 D368 L369 G370 A372 L43 F56 E59 V72 F74 L87 D156 L157 G158 A160 D349 K351 D353 N354 D368 K375 T386 D137 K139 D141 N142 D156 K163 T165 2.7.11.1 0004672,0005524,0006468 Kd=4.4uM IC50=420nM Q9H4A3 27712055 501 KAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKGTPEFMAPEMYAAAYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEET 5tf9 A 2.5 BS02 ANP A 1 G228 G230 K233 A248 M304 K351 G19 G21 K24 A39 M92 K139 D349 K351 D353 N354 D368 K375 T386 D137 K139 D141 N142 D156 K163 T165 2.7.11.1 0004672,0005524,0006468 Q9H4A3 27712055 502 KAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKGTPEFMAPEMYAAAYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEET 5tf9 A 2.5 BS03 MN A 1 N354 D368 N142 D156 D349 K351 D353 N354 D368 K375 T386 D137 K139 D141 N142 D156 K163 T165 2.7.11.1 0004672,0005524,0006468 Q9H4A3 27712055 503 KAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKGTPEFMAPEMYAAAYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEET 5tf9 A 2.5 BS04 CA A 1 S423 C425 S202 C204 D349 K351 D353 N354 D368 K375 T386 D137 K139 D141 N142 D156 K163 T165 2.7.11.1 0004672,0005524,0006468 Q9H4A3 27712055 504 KAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKCIVLVTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKGTPEFMAPEMYAAAYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQEET