5te8 A 2.7 BS01 HEM A 1 R105 I118 W126 R130 F302 A305 T309 L373 R375 P434 F435 G436 R440 N441 C442 I443 F447 A448 M452 R84 I97 W105 R109 F275 A278 T282 L346 R348 P407 F408 G409 R413 N414 C415 I416 F420 A421 M425 T309 F435 C442 T282 F408 C415 1.14.14.1,1.14.14.55,1.14.14.56,1.14.14.73 0002933,0004497,0005496,0005506,0005515,0005737,0005783,0005789,0006629,0006631,0006694,0006706,0006805,0008202,0008203,0008209,0008210,0008395,0008401,0009822,0016020,0016098,0016491,0016705,0016712,0019825,0019899,0020037,0030343,0034875,0036378,0042178,0042359,0042369,0042572,0042573,0042759,0043231,0046222,0046872,0050591,0050649,0062181,0062187,0062188,0062189,0070330,0070576,0070989,0101020,0101021,0102320 P08684 28031486 601 AYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLDTQKHRVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD 5te8 A 2.7 BS02 08J A 1 R105 S119 L216 A305 T309 I369 G481 L482 R84 S98 L195 A278 T282 I342 G454 L455 T309 F435 C442 T282 F408 C415 1.14.14.1,1.14.14.55,1.14.14.56,1.14.14.73 0002933,0004497,0005496,0005506,0005515,0005737,0005783,0005789,0006629,0006631,0006694,0006706,0006805,0008202,0008203,0008209,0008210,0008395,0008401,0009822,0016020,0016098,0016491,0016705,0016712,0019825,0019899,0020037,0030343,0034875,0036378,0042178,0042359,0042369,0042572,0042573,0042759,0043231,0046222,0046872,0050591,0050649,0062181,0062187,0062188,0062189,0070330,0070576,0070989,0101020,0101021,0102320 IC50=8100nM, Ki=2470nM P08684 28031486 602 AYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFFLSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLDTQKHRVDFLQLMIDSQNSHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRD