5obr A 2.62 BS01 9QT A 1 K166 E175 L178 R179 Y199 H201 V206 K41 E50 L53 R54 Y74 H76 V81 D256 K258 E260 N261 D274 T292 D131 K133 E135 N136 D149 T157 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 -logKd/Ki=5.36, Ki=4.4uM O14965 28787041 401 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP 5obr A 2.62 BS02 SKE A 1 R137 L139 V147 A160 E211 A213 G216 L263 R12 L14 V22 A35 E86 A88 G91 L138 D256 K258 E260 N261 D274 T292 D131 K133 E135 N136 D149 T157 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 Kd=250nM, IC50=11nM O14965 28787041 402 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP