5lhi A 3.4 BS01 FAD A 1 G285 G287 S289 E308 A309 R310 G315 R316 G330 A331 M332 V333 A589 V590 T624 L625 P626 W756 S760 Y761 G800 E801 T810 V811 G115 G117 S119 E138 A139 R140 G145 R146 G160 A161 M162 V163 A419 V420 T454 L455 P456 W586 S590 Y591 G630 E631 T640 V641 T335 T165 1.14.99.66 0000122,0000781,0000785,0002039,0002052,0003682,0003713,0005515,0005634,0005654,0005667,0005694,0006325,0006338,0006355,0006357,0006482,0010569,0010718,0010976,0014070,0016491,0019899,0021987,0030374,0031398,0032091,0032451,0032452,0032453,0032454,0032880,0032991,0034644,0036211,0042162,0042551,0042802,0043392,0043426,0043433,0043518,0045793,0045892,0045944,0046098,0050660,0050681,0055001,0060765,0060992,0061629,0061752,0071320,0071480,0090308,0120162,0140297,0140682,0140861,1902166,1990391,1990841,2000179,2000648 O60341 28186757 901 PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTL 5lhi A 3.4 BS02 6X5 A 1 V333 Q358 F538 A539 D555 H564 W695 Y761 A809 V163 Q188 F368 A369 D385 H394 W525 Y591 A639 T335 T165 1.14.99.66 0000122,0000781,0000785,0002039,0002052,0003682,0003713,0005515,0005634,0005654,0005667,0005694,0006325,0006338,0006355,0006357,0006482,0010569,0010718,0010976,0014070,0016491,0019899,0021987,0030374,0031398,0032091,0032451,0032452,0032453,0032454,0032880,0032991,0034644,0036211,0042162,0042551,0042802,0043392,0043426,0043433,0043518,0045793,0045892,0045944,0046098,0050660,0050681,0055001,0060765,0060992,0061629,0061752,0071320,0071480,0090308,0120162,0140297,0140682,0140861,1902166,1990391,1990841,2000179,2000648 -logKd/Ki=8.11, IC50=7.8nM IC50=7.8nM O60341 28186757 902 PSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTL