5jyy A 2.1 BS01 CA A 1 D213 G217 D244 N266 D213 G217 D244 N266 D70 E197 K212 R290 Y324 D70 E197 K212 R290 Y324 3.2.1.18 0004308,0005975,0016020,0033644,0046761,0055036 R4NFR6 27341624 512 RNFNNLTKGLCTINSWHIYGKDNAVRIGESSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKSRMSICISGPNNNASAVVWYNRRPVAEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPADTRIYYFKEGKILKWESLTGTAKHIEECSCYGERTGITCTCKDNWQGSNRPVIQIDPVAMTHTSQYICSPVLTDNPRPNDPNIGKCNDPYPGNNNNGVKGFSYLDGANTWLGRTISTASRSGYEMLKVPNALTDDRSKPIQGQTIVLNADWSGYSGSFMDYWAEGDCYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL 5jyy A 2.1 BS02 6PY A 1 R37 E38 D70 R71 W98 I142 E147 A166 E196 K212 R290 Y324 R37 E38 D70 R71 W98 I142 E147 A166 E196 K212 R290 Y324 D70 E197 K212 R290 Y324 D70 E197 K212 R290 Y324 3.2.1.18 0004308,0005975,0016020,0033644,0046761,0055036 -logKd/Ki=8.10, IC50=8nM R4NFR6 27341624 513 RNFNNLTKGLCTINSWHIYGKDNAVRIGESSDVLVTREPYVSCDPDECRFYALSQGTTIRGKHSNGTIHDRSQYRALISWPLSSPPTVYNSRVECIGWSSTSCHDGKSRMSICISGPNNNASAVVWYNRRPVAEINTWARNILRTQESECVCHNGVCPVVFTDGSATGPADTRIYYFKEGKILKWESLTGTAKHIEECSCYGERTGITCTCKDNWQGSNRPVIQIDPVAMTHTSQYICSPVLTDNPRPNDPNIGKCNDPYPGNNNNGVKGFSYLDGANTWLGRTISTASRSGYEMLKVPNALTDDRSKPIQGQTIVLNADWSGYSGSFMDYWAEGDCYRACFYVELIRGRPKEDKVWWTSNSIVSMCSSTEFLGQWNWPDGAKIEYFL