5he2 A 2.79 BS01 F0S A 1 I197 R199 G200 F202 G203 A218 L222 M274 L324 S334 D335 G337 L338 I168 R170 G171 F173 G174 A189 L193 M245 L295 S305 D306 G308 L309 D317 K319 N322 D335 K344 T353 D288 K290 N293 D306 K315 T324 2.7.11.15 0001664,0002026,0002029,0002031,0003108,0004672,0004674,0004703,0005515,0005524,0005737,0005829,0005886,0006468,0006886,0007165,0007186,0007213,0009966,0016020,0016310,0018105,0031694,0031755,0042995,0045202,0045880,0045988,0047696,0060048,0098793,0098794,1901081,1903566 -logKd/Ki=6.89, IC50=0.13uM IC50=130nM P21146 27050625 701 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP