5a8z A 2.0 BS01 FUC B 1 W27 Q135 V200 C201 N202 G207 W12 Q121 V175 C176 N177 G178 H57 D102 G189 C191 F192 G193 D194 S195 G196 H41 D88 G164 C166 F167 G168 D169 S170 G171 3.4.21.37 0000122,0001878,0002020,0002438,0002523,0002812,0003714,0004175,0004252,0005515,0005576,0005615,0005737,0005829,0006508,0006874,0006909,0008201,0008233,0008236,0009411,0009986,0017053,0019955,0022617,0030141,0030163,0031410,0032496,0032682,0032717,0032757,0035578,0035580,0042742,0043406,0045335,0048661,0050728,0050778,0050832,0050900,0050922,0062023,0070062,0070269,0070945,0070947,1903238 P08246 26333652 2 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 5a8z A 2.0 BS02 FUC C 1 V64 R65 V51 R52 H57 D102 G189 C191 F192 G193 D194 S195 G196 H41 D88 G164 C166 F167 G168 D169 S170 G171 3.4.21.37 0000122,0001878,0002020,0002438,0002523,0002812,0003714,0004175,0004252,0005515,0005576,0005615,0005737,0005829,0006508,0006874,0006909,0008201,0008233,0008236,0009411,0009986,0017053,0019955,0022617,0030141,0030163,0031410,0032496,0032682,0032717,0032757,0035578,0035580,0042742,0043406,0045335,0048661,0050728,0050778,0050832,0050900,0050922,0062023,0070062,0070269,0070945,0070947,1903238 P08246 26333652 2 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 5a8z A 2.0 BS03 IUL A 1 H57 Y94 L99 D102 V190 C191 F192 S195 A213 S214 F215 V216 H41 Y80 L85 D88 V165 C166 F167 S170 A184 S185 F186 V187 H57 D102 G189 C191 F192 G193 D194 S195 G196 H41 D88 G164 C166 F167 G168 D169 S170 G171 3.4.21.37 0000122,0001878,0002020,0002438,0002523,0002812,0003714,0004175,0004252,0005515,0005576,0005615,0005737,0005829,0006508,0006874,0006909,0008201,0008233,0008236,0009411,0009986,0017053,0019955,0022617,0030141,0030163,0031410,0032496,0032682,0032717,0032757,0035578,0035580,0042742,0043406,0045335,0048661,0050728,0050778,0050832,0050900,0050922,0062023,0070062,0070269,0070945,0070947,1903238 ic50=28nM -logKd/Ki=7.55, IC50=28nM IC50=28nM P08246 26333652 1001 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ