4yzc A 2.494 BS01 STU A 1 L577 V586 A597 K599 I642 L644 C645 H692 L695 L16 V25 A36 K38 I75 L77 C78 H117 L120 D688 K690 N693 D711 T734 D113 K115 N118 D136 T158 2.7.11.1,3.1.26.- 0004521,0004540,0004672,0004674,0005524,0006397,0006468,0030968 ic50=3nM -logKd/Ki=8.52, IC50=3nM O75460 26438213 1001 SVVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILPDREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILISMPNAHGKIKAMISDFGLCKKLAVRHSFSRRSGVPGTEGWIAPEMLSCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQANILLGACSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLRAMRNKKHHYRELPAEVRETLGSLPDDFVCYFTSRFPHLLAHTYRAMELCSHERLFQPYYFH