4y85 A 2.33 BS01 499 A 1 W132 F143 P145 V152 A165 K167 E208 G210 G213 S214 E217 V260 V269 D270 W52 F60 P62 V69 A82 K84 E125 G127 G130 S131 E134 V177 V186 D187 D253 K255 N258 D270 T290 D170 K172 N175 D187 T207 2.7.11.25 0004672,0005524,0006468 ic50=13nM -logKd/Ki=7.89, IC50=13nM P41279 25918157 401 LSSVRYGTVEDLLAFANHISNTPQESGILLNMVITPQNGRYQIDSDVLLIPWKLTYRNIFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKPSDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMSTKAVLVDFGLSVQMTEDVYFPKDLRGTEIYMSPEVILCRGHSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPLEDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALNP