4y46 A 2.04 BS01 4F2 A 1 I70 A91 M146 M149 A151 Q155 L206 I26 A47 M102 M105 A107 Q111 L162 D189 K191 N194 D207 T226 D145 K147 N150 D163 T180 2.7.11.24 0004672,0004707,0005524,0006468 ic50=11nM -logKd/Ki=7.96, IC50=11nM IC50=11nM P53779 25893042 501 DNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTASFMMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDQLDEREHTIEEWKELIYKEVMN