4wrs A 2.2 BS01 3U1 A 1 L44 G45 F49 A65 E121 R122 V126 D128 E171 L174 I185 L12 G13 F17 A33 E89 R90 V94 D96 E139 L142 I153 D167 K169 N172 D186 L193 T204 D135 K137 N140 D154 L161 T172 2.7.11.1 0004672,0004674,0005524,0006468,0043066 ic50=0.4nM -logKd/Ki=9.40, IC50=0.4nM IC50=0.400000nM P11309 25597005 403 PLESQYQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETAEIHLH