4qtd A 1.5 BS01 38Z A 1 V40 A53 M108 L110 M111 D112 A113 N114 C116 Q117 Q120 S155 N156 L168 V35 A48 M103 L105 M106 D107 A108 N109 C111 Q112 Q115 S150 N151 L163 D151 K153 N156 D169 T188 D146 K148 N151 D164 T180 2.7.11.24 0004672,0004707,0005524,0006468 ic50=1080nM -logKd/Ki=5.97, IC50=1080nM P45983 25195011 424 RDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDL 4qtd A 1.5 BS02 ANP A 1 G35 A36 Q37 K153 S155 N156 T188 G30 A31 Q32 K148 S150 N151 T180 D151 K153 N156 D169 T188 D146 K148 N151 D164 T180 2.7.11.24 0004672,0004707,0005524,0006468 P45983 25195011 425 RDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDL