4kq5 A 2.4 BS01 MG A 1 D103 D107 D95 D99 K57 F98 D103 D107 R112 D174 K200 F239 D243 D244 K49 F90 D95 D99 R104 D166 K192 F231 D235 D236 2.5.1.1,2.5.1.10 0004659,0008299,0016765 P14324 401 VYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFASFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 4kq5 A 2.4 BS02 MG A 2 D103 D107 D95 D99 K57 F98 D103 D107 R112 D174 K200 F239 D243 D244 K49 F90 D95 D99 R104 D166 K192 F231 D235 D236 2.5.1.1,2.5.1.10 0004659,0008299,0016765 P14324 403 VYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFASFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK 4kq5 A 2.4 BS03 ZOL A 1 D103 R112 Q171 K200 T201 D243 K257 D95 R104 Q163 K192 T193 D235 K249 K57 F98 D103 D107 R112 D174 K200 F239 D243 D244 K49 F90 D95 D99 R104 D166 K192 F231 D235 D236 2.5.1.1,2.5.1.10 0004659,0008299,0016765 IC50=100nM, Ki=85.9nM P14324 404 VYAQEKQDFVQHFSQIVRVLTEDEMGHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFASFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYK