4kpd A 1.96 BS01 MG A 1 D103 D107 D91 D95 K57 F98 D103 D107 R112 D174 K200 F239 D243 D244 K45 F86 D91 D95 R100 D162 K188 F227 D231 D232 2.5.1.1,2.5.1.10 0004659,0008299,0016765 P14324 401 VYAQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFFSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK 4kpd A 1.96 BS02 MG A 2 D103 D107 D91 D95 K57 F98 D103 D107 R112 D174 K200 F239 D243 D244 K45 F86 D91 D95 R100 D162 K188 F227 D231 D232 2.5.1.1,2.5.1.10 0004659,0008299,0016765 P14324 403 VYAQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFFSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK 4kpd A 1.96 BS03 IPE A 1 G56 K57 R60 Q96 R113 F204 F239 G44 K45 R48 Q84 R101 F192 F227 K57 F98 D103 D107 R112 D174 K200 F239 D243 D244 K45 F86 D91 D95 R100 D162 K188 F227 D231 D232 2.5.1.1,2.5.1.10 0004659,0008299,0016765 P14324 404 VYAQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFFSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK 4kpd A 1.96 BS04 RIS A 1 D103 R112 Q171 K200 T201 D243 K257 D91 R100 Q159 K188 T189 D231 K245 K57 F98 D103 D107 R112 D174 K200 F239 D243 D244 K45 F86 D91 D95 R100 D162 K188 F227 D231 D232 2.5.1.1,2.5.1.10 0004659,0008299,0016765 IC50=11nM, Ki=82.2nM P14324 405 VYAQEKQDFVQHFSQIVRVLTEHPEIGDAIARLKEVLEYNAIGGKYNRGLTVVVAFRELVEPRKQDADSLQRAWTVGWCVELLQAFFLVADDIMDSSLTRRGQICWYQKPGVGLDAINDANLLEACIYRLLKLYCREQPYYLNLIELFLQSSYQTEIGQTLDLLTAPQGNVDLVRFTEKRYKSIVKYKTAFFSFYLPIAAAMYMAGIDGEKEHANAKKILLEMGEFFQIQDDYLDLFGDPSVTGKIGTDIQDNKCSWLVVQCLQRATPEQYQILKENYGQKEAEKVARVKALYEELDLPAVFLQYEEDSYSHIMALIEQYAAPLPPAVFLGLARKIYKRRK