4kc2 A 1.7 BS01 BHE A 1 H233 F236 T245 W300 E303 D326 H176 F179 T188 W243 E246 D269 H233 G266 W300 E303 A343 H176 G209 W243 E246 A286 2.4.1.37,2.4.1.40 0005975,0016020,0016758 P16442 24108680 402 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYGGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPK 4kc2 A 1.7 BS02 WS2 A 1 F121 A122 I123 Y126 W181 V184 R188 D211 V212 D213 F64 A65 I66 Y69 W124 V127 R131 D154 V155 D156 H233 G266 W300 E303 A343 H176 G209 W243 E246 A286 2.4.1.37,2.4.1.40 0005975,0016020,0016758 -logKd/Ki=3.31, IC50=493uM P16442 24108680 403 AIGEFMVSLPRMVYPQPKVLTPCRKDVLVVTPWLAPIVWEGTFNIDILNEQFRLQNTTIGLTVFAIKKYVAFLKLFLETAEKHFMVGHRVHYYVFTDQPAAVPRVTLGTGRQLSVLEVRAYKRWQDVSMRRMEMISDFCERRFLSEVDYLVCVDVDMEFRDHVGVEILTPLFGTLHPGFYGSSREAFTYERRPQSQAYIPKDEGDFYYGGAFFGGSVQEVQRLTRACHQAMMVDQANGIEAVWHDESHLNKYLLRHKPTKVLSPEYLWDQQLLGWPAVLRKLRFTAVPK