4k69 A 1.5 BS01 ZN A 1 H25 E78 H10 E64 H57 D102 K192 G193 D194 S195 G196 H45 D89 K168 G169 D170 S171 G172 3.4.21.39 0002003,0004175,0004252,0005576,0005615,0005737,0005829,0006508,0006518,0008236,0016485,0022617,0030141,0030163,0030901,0034769,0036464,0042277,0043231,0045766,0050727,0062023,0071333,0140447 P23946 23659209 301 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGAAQGIVSYGRSDAKPPAVFTRISHYQPWINQILQAN 4k69 A 1.5 BS02 ZN A 2 H101 H233 H88 H203 H57 D102 K192 G193 D194 S195 G196 H45 D89 K168 G169 D170 S171 G172 3.4.21.39 0002003,0004175,0004252,0005576,0005615,0005737,0005829,0006508,0006518,0008236,0016485,0022617,0030141,0030163,0030901,0034769,0036464,0042277,0043231,0045766,0050727,0062023,0071333,0140447 P23946 23659209 302 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGAAQGIVSYGRSDAKPPAVFTRISHYQPWINQILQAN 4k69 A 1.5 BS03 1P9 A 1 C42 H57 A190 F191 K192 S195 S214 Y215 G216 C30 H45 A166 F167 K168 S171 S186 Y187 G188 H57 D102 K192 G193 D194 S195 G196 H45 D89 K168 G169 D170 S171 G172 3.4.21.39 0002003,0004175,0004252,0005576,0005615,0005737,0005829,0006508,0006518,0008236,0016485,0022617,0030141,0030163,0030901,0034769,0036464,0042277,0043231,0045766,0050727,0062023,0071333,0140447 ic50=0.04uM -logKd/Ki=7.40, IC50=0.04uM IC50=40nM P23946 23659209 304 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNITEEEDTWQKLEVIKQFRHPKYNTSTLHHDIMLLKLKEKASLTLAVGTLGRMCRVAGWGRTGVLKPGSDTLQEVKLRLMDPQACSHFRDFDHNLQLCVGNPRKTKSAFKGDSGGPLLCAGAAQGIVSYGRSDAKPPAVFTRISHYQPWINQILQAN