4jbp A 2.45 BS01 YPH A 1 R137 L139 F144 V147 A160 K162 L164 L169 L178 E181 E211 A213 P214 L215 G216 K224 L263 D274 R12 L14 F19 V22 A35 K37 L39 L44 L53 E56 E86 A88 P89 L90 G91 K99 L138 D149 D256 K258 E260 N261 D274 T292 D131 K133 E135 N136 D149 T157 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 ic50=41nM -logKd/Ki=7.39, IC50=41nM IC50=41nM O14965 23610398 501 RQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP