4j8m A 1.853 BS01 CJ5 A 1 G145 N146 V147 K162 L164 L194 E211 Y212 A213 G216 L263 D274 V279 A281 P282 G21 N22 V23 K38 L40 L70 E87 Y88 A89 G92 L139 D150 V155 A157 P158 D256 K258 E260 N261 D274 T292 D132 K134 E136 N137 D150 T168 2.7.11.1 0000212,0000226,0000278,0004672,0005524,0006468,0007052,0007098,0007100,0051321 ic50=48nM -logKd/Ki=7.32, IC50=48nM O14965 25175806 501 KRQWALEDFEIGRPLGKGKFGNVYLAREKQSKFILALKVLFKAQLEKAGVEHQLRREVEIQSHLRHPNILRLYGYFHDATRVYLILEYAPLGTVYRELQKLSKFDEQRTATYITELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWSVHAPSSRRDTLCGTLDYLPPEMIEGRMHDEKVDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVTEGARDLISRLLKHNPSQRPMLREVLEHPWITANSSKP