4ith A 2.25 BS01 RCM A 1 M67 L70 V75 V76 M92 H136 I154 A155 D156 S161 F162 M39 L42 V47 V48 M64 H108 I126 A127 D128 S133 F134 D138 K140 E142 N143 D156 T189 D110 K112 E114 N115 D128 T142 2.7.11.1 0004672,0005524,0006468 ic50=0.3169uM -logKd/Ki=6.50, IC50=316.9nM IC50=200nM, EC50=18nM Q13546 23473668 307 NVIKMKSSDFLVSLAFHRTQGLMIMKTVNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMAYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAIAEQQLIMAIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLE